TRPM2 and Parkinson disease: In addition, despite being different from their controls, the area and perimeter of the TRPM2+/− PD (Area: p = 0.000; Perimeter: p = 0.000) and TRPM2−/− PD (Area: p = 0.000; Perimeter: p = 0.000) male group were higher than the TRPM2+/+ PD group, as well as for almost all of the parameters assessed.