In addition, we observed that the knockdown of lncRNA STEAP3-AS1 together with STEAP3 significantly inhibited the proliferation and migration of colon cancer cells (Fig. 6K and L, Figure S6H and I), whereas the overexpression of the lncRNA STEAP3-AS1 significantly promoted the proliferation and migration of colon cancer cells (Fig. 6M and N, Figure S6J and K). Here, STEAP3 is linked to malignant colon neoplasm.