SMARCA4 and breast cancer: The study also revealed that the lncRNA TGFB2-AS1 interacts with brahma-related gene-1 (BRG1) and blocks the ability of the chromatin remodelling complex to approach its target promoters both in cis and in trans, thus inhibiting the expression of the target genes TGFB2 and SOX2, and eventually leading to the inhibition of breast cancer progression and lung metastasis [8].