Interestingly, the results were consistent with those of the liver injection experiments, and lncRNA STEAP3-AS1 knockdown significantly inhibited the liver metastasis of colorectal cancer (Fig. 1J) and thereby increased the survival time of nude mice, indicating that inhibiting the lncRNA STEAP3-AS1 significantly inhibited the targeted liver metastasis of CRC (Fig. 1K and L). This evidence concerns the gene STEAP3 and colorectal cancer.