PLK1 and non-small cell lung carcinoma: To further analyze the function of the TET2-BACH1-PRC1 axis in NSCLC progression, the H1299 and H1975 cells were exposed to the TET2 antagonist Bobcat339, the BACH1 antagonist HPPE, or PLK1-IN-10, an antagonist targets PLK1 to limit the PLK1-PRC1 interaction.