The first markers of pulmonary fibrosis were detected at this timepoint, including indolethylamine N-methyltransferase (+4.17 fold), associated with myofibroblast formation [94,95], nestin (+4.17 fold), which is expressed in myofibroblasts and has a pro-fibrotic function by facilitating Rab11-dependent recycling of TGF-β receptor I [96]. This evidence concerns the gene NES and pulmonary fibrosis.