Significant risk factors for mortality were higher age, frailty (indicated by lower creatinine, blood urea nitrogen, and albumin), cardiovascular diseases (history of myocardial infarction, coronary heart disease, cerebrovascular disease, peripheral arterial disease), and greater signs of inflammation (high C-reactive protein, high interleukin 6, higher leukocytes), as shown in Table 2. The gene discussed is ALB; the disease is cerebrovascular disorder.