ARRDC3 and peripheral arterial disease: In addition, there are proteins that were associated with both diseases but exhibited substantially higher effect sizes in one disease compared to the other: SUMF1 (βPD = 0.77, PPD = 2.3 × 10−54; βAD = 0.08, PAD = 3.1 × 10−3) and ARRDC3 (βPD = 0.80, PPD = 8.9 × 10−82; βAD = 0.22, PAD = 9.1 × 10−22).