PSMC5 and Parkinson disease: Proteins central to mitochondrial dysfunction and proteasomal degradation, including PSMC5 (βPD = 0.36, PPD = 1.4 × 10−56; βAD = 0.04, PAD = 4.1 × 10−3) and HGS (βPD = −0.35, PPD = 2.1 × 10−118; βAD = −0.09, PAD = 4.5 × 10−24), also showed higher effect size in PD.