AKT1 and cancer: For pHV infected cells, GO term analysis of the upregulated DEG also identified pathways involving chemotaxis (n = 23 genes) and cancer signalling pathways (n = 36 genes), including NF-kB (n = 69 genes), MAPK (n = 54 genes), Wnt (n = 39 genes), JNK (n = 38 genes) and PI3K/AKT.