S1PR1 and Alzheimer disease: Bioelectricity-related genes that were overexpressed in neurons exposed to bacteria including Apoe (for the protein apolipoprotein E, closely related to Alzheimer ́s disease), S1pr1 (sphingosine-1-phosphate receptor 1, implied in cell–cell adhesion, localized in astrocytes), Slc8b1 (solute carrier family 8 member B1, belongs to a family of potassium-dependent sodium/calcium exchangers), or Alp1 (arginine permease ALP1, enables basic amino acid transmembrane transporter activity).