In the UKB, among individuals with both in-patient and primary care records, we found that 1/6 (17%) heterozygotes had an ICD-10 code directly suggestive of diagnosis of ADH1 (hypocalcemia, disorder of calcium/phosphorous metabolism, or hypoparathyroidism), despite the high frequency of hypocalcemia observed based on calcium measurements, with 6/10 (60%) heterozygotes at or below the serum calcium LLN. The gene discussed is ADH1A; the disease is hypoparathyroidism.