After separate housing in addition to distinct microbiome differences associated with NFAT5 expression, our findings from separate housing and cohousing experiments using FMT from Nfat5+/– mice into Nfat5+/– mice resulted in higher colitis severity than that observed in WT (Nfat5+/+) mice (Figure 3, G–I). This evidence concerns the gene NFAT5 and colitis.