Consistent findings have been reported in otherstudies, where metallosalens were shown to induce apoptosis and exhibitstrong cytotoxicity against cultured cancer cells.−, , ,  Most importantly, the Pt metallosalens (PtL1 and PtL2) under study and PdL2 demonstratedselective induction of apoptosis in cancer cells, highlighting theirstrong potential as novel anticancer agents. The gene discussed is PDCD1LG2; the disease is cancer.