Further, KPD patients can often achieve partial remission: after a few weeks or months of treatment with insulin, they are no longer dependent on insulin and can control blood glucose with diet or oral antidiabetic agents (Mauvais-Jarvis et al., 2004b; McFarlane et al., 2001; Vellanki et al., 2016; Umpierrez et al., 1997; Vellanki et al., 2020). Here, INS is linked to diabetic ketoacidosis.