Research has indicated that the mesenchymal‐epithelial transition factor (MET) plays a critical role in the proliferation, survival, migration, invasion, and therapeutic resistance and recurrence of glioblastomas [31] Bioinformatics predictions have shown that ApoE has a positive correlation with TSC2 and a negative correlation with ATRX, BRAF and MET. This evidence concerns the gene ATRX and glioblastoma.