ESR1 and cancer: We detected selective expression of EphA5 on the membrane and in the cytoplasm of cancer cells of both estrogen receptor-positive and TNBC (Figure 1A), lung squamous cell carcinomas, and lung adenocarcinomas (Figure 1B), as well as colon, pancreatic, gastric, ovarian, and urothelial cancers (Figure 1, C and D).