After aSAH in mice, the number of microglia increases rapidly.29 In rodents, acute TSPO binding increases with SAH severity, and TSPO is related to upregulation of markers of activated microglia and astrocytes.30 Morphologically, these microglia assume a more pro-inflammatory state in the first days after aSAH, shifting to an anti-inflammatory state at a later stage.29 Our findings did not show evidence that long-term inflammation plays a role in the pathophysiology of cognitive impairment following aSAH. This evidence concerns the gene TSPO and Cognitive impairment.