METTL3 and atherosclerosis: In addition, Dong et al. (113) explored the role and molecular mechanism of m6A-METTL3 in a mouse model of atherosclerosis, which showed that the knockdown of METTL3 inhibited the development of endothelial atherosclerosis through the Janus Kinase 2/Signal Transducer and Activator of Transcription 3 (JAK2/STAT3) pathway and IGF2BP1, thus preventing the progression of atherosclerosis.