Chien et al. (73) found that METTL3 could effectively inhibit TNF-α-mediated phosphorylation of p65 in endothelial cells, inhibit the nuclear transcription factor κB (NF-κB) inflammatory pathway to reduce the inflammatory response of endothelial cells, and effectively inhibit the adhesion of monocytes to endothelial cells, thereby suppressing the development of atherosclerosis. The gene discussed is NFKB1; the disease is atherosclerosis.