POU2F1 and Mobius syndrome: Although variants in 8 (USP15, PALM, CNTRL, ZNF407, PBXIP1, ZRANB1, POU2F1, and MINDY1) have been implicated in neurodevelopmental phenotypes and variants in 3 (KCNAB2, KPNA3, and MORC2) in neurological phenotypes (Supplemental Table 10), none of the reported individuals harboring these variants met criteria for MBS.