CRP and asthma: Moreover, it has been found that elevated levels of CRP are associated with vascular inflammation and cardiovascular morbidity in asthma because people who have severe asthma are most likely to suffer from other complications like heart diseases, etc. Airway remodeling is considered an integral feature of asthma and is characterized by wall thickening, smooth muscle hypertrophy in the airway walls, and increased extracellular matrix deposition (39).