Similar results were observed for proximal tubule injury markers Havcr1 and Lcn2, as well as the distal tubule injury marker Lcn2 and the pro-inflammatory cytokines Ifng and Il6. In contrast, the ischemia-reperfusion kidney injury model (IRI) did not recapitulate changes in the genes associated with the differentiation and function of tubules and glomeruli, and most kidney injury markers were unaffected. This evidence concerns the gene IFNG and medical procedure.