Our findings revealed good diagnostic value, with AUCs of 0.93 (95%CI: 0.89–0.98) for anti-Dsg1/anti-Dsg3 and 0.87 (95%CI: 0.82–0.92) for anti-BP180/anti-BP230 in differentiating pemphigus and BP, consistent with prior studies (2, 28). This evidence concerns the gene DST and pemphigus.