ESR1 and cancer: As stated earlier in vivo or in vitro animal research investigations, the majority of these operations have been determined, polysaccharides of mushrooms are starting to be assessed as an adjuvant cancer treatment component next to common cancer care (Narayanan et al. 2023), specifically with patients who have breast cancer with estrogen‐receptor‐positive tumor in which the extracted material of these foods is appeared for suppressing the aromatase action (Gong et al. 2023) and consecutive decrease of estrogen levels.