For example, sesamin, a major lignin from sesame seeds, reduced cell viability in several human breast cancer cells such as the MCF‐7 cell line (Sohel et al. 2022), and α‐mangostin from ethanolic extracts of mangosteen induced apoptosis and suppressed migration and invasion through the PI3K/Akt signaling pathway in the breast cancer cell line MDA‐MB‐231 (Zhu et al. 2021). The gene discussed is AKT1; the disease is breast carcinoma.