Lycopene inhibited colon cancer propagation by suppressing leptin‐mediated cell invasion, Akt activation, MMP‐7 expression, glycogen synthase kinase‐3β (GSK‐3β), ERK 1/2 proteins, AP‐1, and β‐catenin protein levels (Chang et al. 2020). Here, AKT1 is linked to colonic neoplasm.