CEACAM6, a key member of the immunoglobulin superfamily and a nonspecific cross-antigen, may play a synergistic role with various proteins such as ITGB1 and CYR62 in promoting tumor growth, proliferation, migration, and angiogenesis, contributing to CRC occurrence and development (31–33). The gene discussed is CEACAM6; the disease is colorectal carcinoma.