DMD results from loss-of-function mutations in the dystrophin (DMD) gene, leading to the absence of dystrophin, a critical cytoskeletal protein that connects the intracellular actin cytoskeleton to the extracellular matrix via the dystrophin-associated protein complex (DAPC) (Duan et al., n.d.). Here, DNM2 is linked to Duchenne muscular dystrophy.