Consistent with the link between GVBs and tau pathology, we observed a significant and positive correlation of pS106-Rab12 GVB-like cell density with Thal amyloid, Braak tangle, and CERAD neuritic plaque stages in the hippocampus of DLB and AD cases (Fig. 2c-e). The gene discussed is MAPT; the disease is Alzheimer disease.