We also observed pS106-Rab12 labeling of Lewy bodies in LRRK2GS PD and iPD cases (Fig. 8a), although this was not observed in LRRK2GS PD (Braak ≤ 3) cases, likely due to 3 out of 4 of these cases lacking neocortical Lewy bodies (Supplementary Tables 3-4). This evidence concerns the gene RAB12 and Parkinson disease.