RAB12 and Lewy body dementia: We observed pS106-Rab12 labeling features highly reminiscent of granulovacuolar degeneration bodies (GVBs) across subjects (Fig. 2a), with significantly higher pS106-Rab12 GVB-like cell density in subjects with DLB when stratified by Braak neurofibrillary tangle stage (Braak > 3), relative to DLB (Braak ≤ 3) or control cases (Fig. 2a, b).