There were also more GFAP+ astrocytes in the peri-atrophic region of old stroke mice than young stroke mice (p=0.049, Supplementary Fig. 9a & c); more GFAP+ astrocytes in the ipsilateral hippocampi of old stroke mice than young stroke mice (p =0.037, Supplementary Fig. 9b & d). The gene discussed is GFAP; the disease is stroke disorder.