Go analyses showed that after ischemic stroke injury, the leukocyte-mediated immunity, lymphocyte-mediated immunity, glutathione transferase activity, glutathione peroxidase activity, antioxidant activity, peroxidases activity, oxidoreductases activity, acting on peroxide as acceptor, and glycosaminoglycan binding were increased in the ipsilateral cortex of old mice compared to young mice (Fig. 7l). The gene discussed is HPGDS; the disease is ischemic stroke.