MTOR and inflammatory bowel disease: In colonocytes from IBD biopsies, we observed a depletion in protein exporter gene SLC40A1 and enrichment in genes associated with cell proliferation and migration including MTOR (mammalian target of rapamycin), LGALS3 (lectin, galactoside-binding, soluble, 3) and TIMP1 (TIMP metallopeptidase inhibitor 1) (Fig. 2C).