APOE, ABCA1, and ABCG1 proteins were also found in human GBM specimens (Fig. S3C-E), and like in our murine model, significant positive correlations between these lipid trafficking genes and different markers of macrophages and MDSCs were identified in GBM patients (Fig 3K, L, S3F-I). Here, APOE is linked to glioblastoma.