Inhibiting tubulin-β polymerization causes mitotic arrest and apoptosis in cancer cells, making it a prime cytoskeletal target in cancer therapy.5,6 Aromatase, on the other hand, is a key enzyme in estrogen biosynthesis (catalyzing the final step of estrogen production) and is crucial for the growth of hormone-dependent tumors. This evidence concerns the gene CYP19A1 and cancer.