SLC8A1, CHRM5, HTR6, CACNA1H, GRIN1, PARX2, PDGFRA, GNA14, ADCY4, PLN, NOS2, DRC1, NBAT1, COL23A1, KDR, NGFR, INHA, and other cancer-related genes were upregulated in NRDR-siRNA3 group, whereas TRIM31, LINC01358, PCAT1, DUXAP8 were downregulated. The gene discussed is PLN; the disease is cancer.