In vitro, myricetin treatment of SH-SY5Y neuroblastoma cells exposed to 1-methyl-4-phenylpyridine (MPP+) significantly reduces Fe2+ and ROS levels, activates the NRF2/GPX4 signaling pathway, suppresses neuronal ferroptosis, and mitigates cellular injury (Gu et al., 2024). This evidence concerns the gene NFE2L2 and neuroblastoma.