AOC1 and neoplasm: Moreover, Ding et al.14 identified the role of amine oxidase copper-containing 1 (AOC1) as a tumor suppressor in PCA, suggesting that AOC1‘s regulation by the transcription factor SOX15 may enhance anticancer effects through mechanisms involving reactive oxygen species and ferroptosis.14 This comprehensive understanding of cuproptosis mechanisms provides a foundation for developing targeted therapies aimed at exploiting copper homeostasis in PCA.