and was expressed into CD103 + via tissue TGF-β.[42] It has been discovered that the morbidity of primary dyskinesia in patients with CD4-dominated esophagitis is significantly higher than that in patients with CD8-dominated esophagitis.[43] A hypothesis was then proposed that the evidence above may indirectly support the discovery of this research, which is that HHV 7 U14 may be the risk factor for GERD. The gene discussed is ITGAE; the disease is esophagitis.