Considering the elevated expression of PHGDH, SLC1A5 and SLC38A2 in CRC (Figures 1, 2A, S2A–D, S3 and S8A) and their association with tumour proliferation (Figures 5, S12A–D), metastasis (Figures 2B, S8A,B) and patient prognosis (Figure 4A), we selected these genes for validation in real‐world patient cohorts. Here, SLC1A5 is linked to colorectal carcinoma.