PHGDH and neoplasm: While prior studies established upregulation of PHGDH, PSAT1 and PSPH in certain cancers [3], our pan‐cancer analyses reveal distinct expression of these genes in different tumour types: elevated expression was observed in COAD, DLBC, ESCA, GBM, LGG, LUSC, OV, PRAD, READ, THYM, UCEC and UCS, while suppressed expression was observed in KICH, KIRC, KIRP and LAML (Figure 1 (I)).