ARHGEF5 and bacterial infectious disease: Other members of the ARGHGEF family have been associated with cattle omental fat (ARHGEF5 [91]), resistance to disease and bacterial infection [92] and gastrointestinal parasite resistance in Spanish sheep [93] for ARHGEF17. Based on these findings, we speculated that ARHGEF10L might contribute to higher body size in cattle and should be considered as a candidate gene for body size and growth in cattle.