AD-associated DAM/MgnD exhibited a noteworthy gene signature with high expression levels, including Itgax (integrin subunit alpha x), Clec7a (C-type lectin domain containing 7A), Trem2 (triggering receptor expressed on myeloid cells 2), Apoe (apolipoprotein E), Lpl (lipoprotein lipase) and Cst7 (cystatin 7). This evidence concerns the gene ITGAX and Alzheimer disease.