IL1RL1 and acute myeloid leukemia: To assess the role of IL1RL1 in AML progression in vivo, we injected NOD.Cg-Prkdcscid Il2rgtm1Wjl/SzJ (NSG) mice with IL1RL1-CRISPR/Cas9 KO or WT MOLM14 cells without adoptive T cell transfer (Supplementary Fig. 17A).