Given the patient’s family history of frontotemporal dementia (FTD) in a maternal uncle, the genetic analysis was extended to include the most common genes associated with FTD (TARDBP, GRN, TBK1, CHMP2B, SQSTM1, UBQLN2, VCP and MAPT) but no additional variants of clinical significance were detected. Here, CHMP2B is linked to frontotemporal dementia.