Upregulation of HNF1 homeobox B (HNF1B/HNF-1β) in OCCC cells can induce the expression of nuclear factor kappa B (NF-κB), which then induces the expression of PD-1 and its ligand PD-L1, facilitating the immune escape of tumor cells.11 The gene discussed is HNF1B; the disease is neoplasm.