Of note, the analysis did identify a statistically significant association between knee involvement and elevated C-reactive protein (CRP, odds ratio [OR] 4.3; 95% confidence interval [CI] 1.18–21.0; p = 0.04) and endoscopically active ulcerative colitis (UC) (OR, 5.9; 95% CI, 1.16– 37.0; p = 0.04) [7]. The gene discussed is CRP; the disease is ulcerative colitis.