PTH and osteoporosis: Stimulation of glutamatergic neurons from SFO to PVN can promote the upregulation of serum PTH and facilitate the restoration of bone mass.[14] PTH1‐34 has been shown to increase trabecular bone volume and promote bone formation, while also inhibiting the senescence of astrocytes and the activation of pro‐inflammatory cytokines in the brain.[21] This suggests the potential of PTH as a therapeutic agent for mitigating osteoporosis induced by TBI, highlighting its role as a promising treatment option for both conditions.