For example, miRNA‐26 and miRNA‐21 mediated GBM angiogenesis; miRNA‐10 mediated immune escape of GBM cells; circ‐MMP1 mediated tumor invasion and metastasis; and lnc‐CCAT2 mediated neuroinflammation.[21] Therefore, targeting non‐coding RNAs is also an important way for the treatment of CNS diseases. This evidence concerns the gene MMP1 and glioblastoma.