SNCA is the main gene encoding α‐synuclein, and mutations in it can lead to abnormal accumulation and misfolding of α‐synuclein, thereby accelerating the pathological process of PD.[91] Thus, targeting mutant genes significantly inhibits the production of pathogenic proteins and thus improves the prognosis of neurodegenerative diseases. The gene discussed is SNCA; the disease is neurodegenerative disease.