CDKN1B and myopia: Zhang et al. reported that in LIM guinea pigs, the miR-15b-5p/miR-379-3p/IGF1R/PTEN/forkhead box (FOXO)/cyclin-dependent kinase inhibitor 1B (CDKN1B) axis can block the G1 cell cycle, induce apoptosis, affect the process of scleral fibrosis, lead to scleral reshaping, and aggravate the development of myopia 66.