However, recent studies have uncovered a counter-regulatory mechanism involving microRNA-216a-3p (miR-216a-3p), which acts as a tumor suppressor by targeting ACTL6A.99 miR-216a-3p levels inversely correlate with ACTL6A expression in cervical cancer tissues, and its overexpression inhibits cell proliferation, invasion, and EMT.99 Mechanistically, miR-216a-3p directly binds to the ACTL6A 3'-UTR, reducing its protein abundance. Here, ACTL6A is linked to cervical cancer.