CD47 is a pentameric transmembrane glycoprotein expressed on all normal cells,[187, 197] yet it exhibits significantly elevated levels in various cancers, such as myeloid leukemia, bladder cancers, neuroblastoma, non‐Hodgkin's lymphoma, and ovarian cancer, correlating with poor prognosis.[200, 201, 202] Functioning as a “do not eat me” signal, CD47 engages with signaling regulatory protein α (SIRPα) to phosphorylate tyrosine kinase within the phagocyte's cytoplasmic domain. This evidence concerns the gene CD47 and myeloid leukemia.