Figure27a depicts the scheme developed by Chang et al.[183] which suggests combining Ti3C2‐MXene‐Au nanomedicine with OX40 mAb to create a triad of enzyme dynamic/photothermal/antitumor immune synergistic therapy for TNBC[184] Ti3C2‐MXene‐Au nanocomposites were able to build up at the tumor tissue following biodistribution from IV administration and attained PA/thermal dual‐modality imaging in vivo in the interim, owing to the improved retention and permeability effect (EPR) for nanostructures. This evidence concerns the gene TNFRSF4 and neoplasm.