Understanding PCNA’s interactome is essentialdue to its critical role in DNA replication, repair, cell cycle regulation,invasiveness, and stemness offering deeper insights into tumor biology.The PPI network of PCNA, and its top 50 binding proteins, was generatedusing STRING data (high confidence, 0.7) and visualized in Cytoscapeto ascertain its engagement in complex regulatory mechanisms involvinginteractors that contribute to tumor progression (Figure S2a). Here, PCNA is linked to neoplasm.