PCNA and cancer: As the survival data suggests PCNA as a prognosticator,it emerges as an appealing therapeutic target in cancer treatment.Current developments provide persuasive evidence to establish PCNAas the druggable target, with studies demonstrating its selectivetargeting in cancer cells., For instance, small-moleculesinhibitors of PCNA such as ATX-101 and AOH1996 are currently undertakingphase I clinical testing for anticancer therapy without any harmfuleffects on normal healthy cells.−,