In response to oxidative stress,several studies target the Nrf2 signaling pathway for potential antioxidativestrategies for PD. Neuroinflammationis found to be one of the key factors leading to PD pathogenesis, which suggests the suppression of neuroinflammationas one of the therapeutic approaches., Our predictionssuggested several inflammatory-related targets as potential targetsfor the investigated triazoles such as NFKB1, PTGS2 (or COX-2), MAPK8(or JNK1), and MAPK14 (or p38). The gene discussed is MAPK8; the disease is Parkinson disease.