Overthe past decade, evidence has emerged that cytochrome c plays a crucial global role in normal and cancer cellmetabolism.−, ,−, , , , , , ,  In the paper, we showed functional diversity of cytochrome c in the mitochondria, ER, lipid droplets, cytoplasm, andnucleus upon incubation with retinoic acid. The gene discussed is CYCS; the disease is cancer.